Re-B Forte Drug Interactions

Pyridoxine decreases the effects of levodopa. Incompatibilities: Levodopa.
Chronic use of loop diuretics may result in thiamine deficiency. Concomitant intake of thiamine with food that contains sulfites may inactive thiamine.
Concomitant intake of thiamine with tea, coffee and decaffeinated coffee may inactive thiamine. This can reversed by taking supplements.
Pyridoxine reduces the effects of levodopa, but this does not occur if a dopa decarboxylase inhibitor is also given pyridoxine reduces the activity of altretamine. It has also been reported to decreased serum concentrations of phenobarbital and phenytoin. Many drugs may increase the requirement of pyridoxine, such drugs include hydralazine, isoniazid, penicillamine and oral contraceptives.
Absorption of vitamin B12 from the gastrointestinal tract may be reduced by neomycin, aminosalicylic acid, histamine H2-antagonists, metformin, para-aminosalicylic acid, potassium chloride, colchicines and proton pump inhibitors (lansoprazole, omeprazole, pantoprazole, rabeprazole), cholestyramine and colestipol may decrease the enterohepatic reabsorption of vitamin B12. Inhalation of the anesthetic agent nitrous oxide can produce a functional vitamin B12 deficiency. The use of antibiotics may alter the intestinal microflora and may decrease the possible contribution of vitamin B12 by certain inhabitants of microflora to the body's requirement.